| TUPELO POTW | MS0036111 | Publicly owned treatment works | Major | DIRECTLY INTO TOWN CREEK |
| ASHLEY FURNITURE INDUSTRIES, LLC, VERONA PLANT 4 | MSR109462 | | Minor | Louisa Creek-Coonewah Creek |
| ATMOS ENERGY CORPORATION, BARNES CROSSING PROJECT | MSR108909 | | Minor | Mud Creek-Town Creek |
| ATMOS ENERGY CORPORATION, COLEY ROAD PROJECT | MSR109244 | | Minor | Kings Creek-Town Creek |
| AUBURN APARTMENTS LLC, GURU PROPERTIES | MS0062499 | | Minor | |
| BARNES CROSSING HYUNDAI MAZDA | MSR108564 | | Minor | Busfaloba Creek-Town Creek |
| BROKEN LIVES MINISTRY | MS0043958 | | Minor | DIRECTLY INTO SOUTH TULIP CREEK |
| BUTLER PARK SUBDIVISION | MSR108761 | | Minor | Little Coonewah Creek-Coonewah Creek |
| CHICKASAW INKANA FOUNDATION, CHICKASAW HERITAGE CENTER | MSR108976 | | Minor | Kings Creek-Town Creek |
| COOK AND SON LLC, EASON BOULEVARD IMPROVEMENTS | MSR108751 | | Minor | Kings Creek-Town Creek |
| COOPER TIRE & RUBBER COMPANY | MSP090763 | | Minor | MS0036111 - TUPELO POTW |
| CROSSLAND CONSTRUCTION COMPANY, TARGET, TUPELO MS | MSR109566 | | Minor | Busfaloba Creek-Town Creek |
| ELVIS PRESLEY LAKE | MS0034444 | | Minor | MIDDLE TULIP CREEK |
| EVANS GENERAL CONTRACTORS, LLC, PROJECT WAYFARER | MSR109336 | | Minor | |
| FLOWERDALE COMMONS 2021 LP | MSR108781 | | Minor | |
| GENLYTE THOMAS GROUP LLC | MSP090285 | | Minor | MS0036111 - CITY OF TUPELO |
| GREAT RIVER UTILITY OPERATING CO LLC, HIGH FOREST SUBDIVISION | MS0047830 | | Minor | REEDS BRANCH |
| ITAWAMBA COMMUNITY COLLEGE, TRUCK DRIVER TRAINING FACILITY | MSR109001 | | Minor | Kings Creek-Town Creek |
| JAI JALARAM INC, SUPER 8 MOTEL | MS0039501 | | Minor | TOWN CREEK |
| JJM PROPERTIES, LLC, MITCHELL ESTATES SUBDIVISION | MSR109469 | | Minor | Louisa Creek-Coonewah Creek |
| JS LLC, HEARD TOWN ESTATES SUBDIVISION | MS0055972 | | Minor | DIRECTLY INTO BUSHFALOBA |
| JS LLC, MT VERNON ESTATES SUBDIVISION | MS0056154 | | Minor | UNNAMED TRIB THEN TOWN CREEK |
| LEE COUNTY BOARD OF SUPERVISORS, LEE COUNTY ADULT DETENTION CENTER | MSR109607 | | Minor | Mud Creek-Town Creek |
| MISS DEPT OF W F & PARKS, TOMBIGBEE STATE PARK | MS0033464 | | Minor | TOWN CREEK |
| MT VERNON PROPERTIES LLC | MSR108765 | | Minor | Kings Creek-Town Creek |
| NATCHEZ TRACE PARKWAY | MS0023302 | | Minor | UNNAMED TRIB THEN MUD CREEK |
| PALMETTO WATER ASSOCIATION, PALMETTO WATER ASSOCIATION SYSTEM IMPROVEMENTS | MSR109265 | | Minor | Chiwapa Creek, then to Coonewah Creek then to Dry |
| PALMETTO WATER ASSOCIATION, PALMETTO WATER ASSOCIATION SYSTEM IMPROVEMENTS | MSR109483 | | Minor | Dry Creek-Chiwapa Creek |
| R K METALS LLC | MSP092008 | | Minor | MS0036111 - TUPELO POTW |
| RENIN US LLC | MSP090372 | | Minor | MS0036111 - CITY OF TUPELO |
| RKH DEVELOPER LLC, THE PRESLEY | MSR108757 | | Minor | Tulip Creek |
| ROGER PARKER, COVE LANE COTTAGES | MS0062391 | | Minor | |
| T & L SPECIALTY COMPANY INC | MSP090541 | | Minor | MS0036111 - TUPELO POTW |
| TECUMSEH PRODUCTS CO, TUPELO DIVISION | MSP090135 | | Minor | MS0042048 - VERONA POTW |
| TENNESSEE VALLEY AUTHORITY, NORTH GREEN STREET DELIVERY POINT PROJECT | MSR109140 | | Minor | Mud Creek-Town Creek |
| THERMOSAFE TECHNOLOGIES INC | MSP090739 | | Minor | MS0036111 - CITY OF TUPELO POTW |
| TIMBERLANE UTILITY LLC. TIMBERLANE SUBDIVISION | MS0056839 | | Minor | DRY CREEK |
| TRIPLE W PROPERTIES LLC | MSR108764 | | Minor | Kings Creek-Town Creek |
| TULIP CREEK 2021 LP, TULIP CREEK APARTMENT HOUSING | MSR108780 | | Minor | |
| TUPELO AIRPORT AUTHORITY | MSR002573 | Industrial stormwater | Minor | Town Creek |
